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Arsenic exposure also hampers glutathione biosynthesis, exacerbating oxidative stress in renal tissues [126]

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3 In mammalian species, the dimeric cytosolic GSTs are abundantly expressed in many tissues and grouped into seven distinct isoenzyme classes termed alpha, pi, mu, omega, sigma, theta and zeta

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ii) neuroendocrine regulation and CRH release affected by chronic stress activate an inflammatory response, affecting the growth of an ectopic endometrium and the physiopathology of the pelvic organs, and leading to exacerbation of symptoms in endometriosis (33, 34)

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